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Pyometra is a pus infection of the uterus.

This is a condition that can arise in any female dog or cat that has not been spayed.
Incidence of pyometra increases with age but can occur as early as the first
“heat”. The telltale signs of this condition include but are not limited to (1) vaginal
discharge that is not associated with “heat” (2) excessive thirst and increased
urination and (3) loss of appetite. Pyometra can be a life-threatening illness.
Treatment involves spaying the affected pet. There are greater risks in spaying a pet
that has developed a pyometra as compared to a healthy pet, however, there are no
other viable alternatives.